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Health status and quality of life in tuberculosis

James BrownCentre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, and Division of Medicine, University College London, Pond Street, London NW3 2QG, UK. Electronic address: [email protected]Santino CapocciCentre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, and Division of Medicine, University College London, Pond Street, London NW3 2QG, UKColette SmithResearch Department of Infection and Population Health, University College London, London, UKSteve MorrisDepartment of Applied Health Research, University College London, London, UKIbrahim AbubakarResearch Department of Infection and Population Health, University College London, London, and Medical Research Council Clinical Trials Unit, London, UKMarc LipmanCentre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, and Division of Medicine, University College London, Pond Street, London NW3 2QG, UK
2015en
ABI

Аннотация

Tuberculosis (TB) is a leading cause of global morbidity, yet there is limited information regarding its impact on quality of life and health status. This is surprising given the implications for patient care, the evaluation of novel treatments or preventative strategies, and also health policy. Furthermore, there is no validated TB-specific instrument that measures health status, and thus a wide and non-standardized range of assessment tools have been employed. The studies to date have chosen a number of different comparator populations, and in many TB endemic areas there is a lack of normative data regarding the health status of the general population. Systematic evaluations of quality of life are urgently needed in specific groups, including those with extrapulmonary TB, drug-resistant disease, HIV co-infection, and latent TB infection, and in children with TB; the assessment of post-treatment disability is also required.

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