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Effectiveness of Repair of Aortic Coarctation in Neonates: A Long-Term experience

Chiara MinottiPediatric Cardiology, Department of Women's and Children's Health, University of Padova, Via Giustiniani 2, 35128, Padova, Italy. [email protected]Manuela ScioniDepartment of Statistical Sciences, University of Padova, Padova, ItalyBiagio CastaldiPediatric Cardiology, Department of Women's and Children's Health, University of Padova, Via Giustiniani 2, 35128, Padova, ItalyAlvise GuarientoDivision of Cardiovascular Surgery, Department of Surgery, Hospital for Sick Children, Toronto, CanadaRoberta BiffantiPediatric Cardiology, Department of Women's and Children's Health, University of Padova, Via Giustiniani 2, 35128, Padova, ItalyGiovanni Di SalvoPediatric Cardiology, Department of Women's and Children's Health, University of Padova, Via Giustiniani 2, 35128, Padova, ItalyVladimiro L. VidaPediatric and Congenital Cardiac Surgery, Department of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, ItalyMassimo A. PadalinoPediatric and Congenital Cardiac Surgery, Department of Cardiothoracic and Vascular Sciences and Public Health, University of Padova, Padova, Italy
2021en
ABI

Аннотация

To evaluate early and long-term results of surgical treatment of aortic coarctation (CoAo) in neonates. This is a retrospective clinical review of neonates with CoAo, who underwent surgery between 1995 and 2019. Data were retrieved from our institutional database, to identify preoperative and postoperative characteristics. Statistical analysis was performed by means of relative risk ratio and Cox and logistic multivariate analysis. 218 consecutive neonates (M/F: 129/89, median age 11 days, IQR 7-17 days) were included; 202 (92.7%) had a left thoracotomy; 178 underwent extended end-to-end anastomosis (EEEA, 81.6%). Hypoplastic aortic arch (HAA) was present in 102 patients (46.8%); complex cardiac anomalies in 85 (39%). Significant postoperative complications occurred in 20 (9.2%). Thirty-day mortality was 2.3% (most in complex types). At a median follow-up of 10.4 years (IQR 5.6-15.0 years; FU completeness 95.9%), there were 8 late deaths (3.7%), all associated to complex CoAo. Among 196 survivors, 177 (93.2%) were in NYHA class I; re-interventions on aortic arch occurred in 9.2% (2.0% were surgical). Freedom from mortality and re-intervention on aorta at 10 years were 94.3% and 96.7%, respectively. Surgical repair of CoAo in newborns without CPB in our series was safe and low-risk, with excellent early and late outcomes.

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