Обзорная статья

Fullerenes for the treatment of cancer: an emerging tool

Neha Benedicta FernandesDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Udupi, Karnataka, IndiaRaghavendra Udaya Kumar ShenoyDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Udupi, Karnataka, IndiaMandira Kashi KajampadyDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Udupi, Karnataka, IndiaCleona E. M. DCruzRupesh Kalidas ShirodkarLalit KumarDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Udupi, Karnataka, India. [email protected]Ruchi VermaDepartment of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Udupi, Karnataka, India

2022en

ABI

Аннотация

Cancer is a most common cause of mortality globally. Available medicines possess severe side effects owing to their non-specific targeting. Hence, there is a need of an alternative in the healthcare system that should have high efficacy with the least side effects, also having the ability to achieve site-specific targeting and be reproducible. This is possible with the help of fullerenes. Fullerenes are having the unique physicochemical and photosensitizer properties. This article discusses the synthesis, functionalization, mechanism, various properties, and applications of C60 fullerenes in the treatment of cancer. The review article also addresses the various factors influencing the activity of fullerenes including the environmental conditions, toxicity profile, and future prospective.

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Идентификаторы

DOI: 10.1007/s11356-022-21449-7

Цитирования и источники

Цитирований: 2Использованных источников: 0

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