Cycloartane Glycosides from the Rhizomes of Cimicifuga racemosa and Their Cytotoxic Activities.
Kazuki WatanabeLaboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life ScienceYoshihiro MimakiLaboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life ScienceHiroshi SakagamiDepartment of Dental Pharmacology, Meikai University School of DentistryYutaka SashidaLaboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science
2002en
ABI
Аннотация
Phytochemical analysis of the rhizomes of Cimicifuga racemosa (Ranunculaceae) resulted in the isolation of twelve cycloartane glycosides (1--12), including four new ones (4--6, 12). The structures of the new compounds were determined by spectroscopic analysis, including two-dimensional (2D) NMR data, and chemical methods. The isolated compounds were evaluated for their cytotoxic activities against human oral squamous cell carcinoma (HSC-2) cells and normal human gingival fibroblasts (HGF).
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