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Toward Chemotactic Supramolecular Nanoparticles: From Autonomous Surface Motion Following Specific Chemical Gradients to Multivalency-Controlled Disassembly

Chiara LionelloDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyAndrea GardinDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyAnnalisa CardelliniDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyDavide BochicchioDepartment of Innovative Technologies, University of Applied Sciences and Arts of Southern Switzerland, Polo Universitario Lugano, Campus Est, Via la Santa 1, 6962 Lugano-Viganello, SwitzerlandManisha ShivrayanDepartment of Chemistry, Center for Bioactive Delivery at the Institute for Applied Life Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United StatesAnn FernandezDepartment of Chemistry, Center for Bioactive Delivery at the Institute for Applied Life Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United StatesS. ThayumanavanDepartment of Chemistry, Center for Bioactive Delivery at the Institute for Applied Life Sciences, University of Massachusetts, Amherst, Massachusetts 01003, United StatesGiovanni M. PavanDepartment of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy
2021en
ABI

Аннотация

experiments provide physical-chemical insights on key molecular features in the self-assembling units which determine the dynamic behavior and fate of the NPs on the surface: from adhesion, to diffusion, and disassembly. This offers a privileged point of view into the chemotactic properties of supramolecular assemblies, improving our knowledge on how to design new types of materials with bioinspired autonomous behaviors.

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