Статья

Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results

Christopher G. GoetzDepartment of Neurological Sciences, Rush University Medical Center, Chicago, Illinois 60612, USA. [email protected]Barbara C. TilleyBiostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South CarolinaStephanie R. ShaftmanBiostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South CarolinaGlenn T. StebbinsDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IllinoisStanley FahnDepartment of Neurology, Columbia University, New York, New YorkPablo Martínez‐MartínNeuroepidemiology Unit and CIBERNED, Carlos III Institute of Health, Madrid, SpainWerner PoeweDepartment of Neurology, Innsbruck Medical University, Innsbruck, AustriaCristina SampaioDepartment of Pharmacology, Faculdade de Medicina de Lisboa, Lisboa, PortugalMatthew B. SternDepartment of Neurology, University of Pennsylvania, Philadelphia, PennsylvaniaRichard DodelDepartment of Neurology, Philipps-University, Marburg, GermanyBruno DuboisDepartment of Neurology, Hôpital de la Salpêtrière, Paris, FranceRobert G. HollowayDepartment of Neurology, University of Rochester, Rochester, New YorkJoseph JankovicDepartment of Neurology, Baylor College of Medicine, Houston, TexasJaime KulisevskyDepartment of Neurology and CIBERNED, Sant Pau Hospital, Barcelona, SpainAnthony E. LangDivision of Neurology, University of Toronto, Toronto, CanadaAndrew J. LeesReta Lila Weston Institute of Neurological Studies, University College, London, EnglandSue E. LeurgansDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IllinoisPeter A. LeWittDepartment of Neurology, Wayne State University, Detroit, MichiganDavid L. NyenhuisDepartment of Neurology and Rehabilitation, University of Illinois, Chicago, IllinoisC. Warren OlanowDepartment of Neurology, Mount Sinai School of Medicine, New York, New YorkOlivier RascolLaboratoire de Pharmacologie Médicale et Clinique, Toulouse University, Toulouse, FranceAnette SchragDepartment of Clinical Neurosciences, University College, London, EnglandJeanne A. TeresiStroud Center, Division of General Medicine and Psychiatric Institute, Columbia University, New York, New YorkJacobus J. van HiltenDepartment of Neurology, Leiden University, Leiden, The NetherlandsNancy R. LaPelleDivision of Preventive and Behavioral Medicine, University of Massachusetts, Worcester, Massachusetts

2008en

ABI

Аннотация

We present a clinimetric assessment of the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS). The MDS-UDPRS Task Force revised and expanded the UPDRS using recommendations from a published critique. The MDS-UPDRS has four parts, namely, I: Non-motor Experiences of Daily Living; II: Motor Experiences of Daily Living; III: Motor Examination; IV: Motor Complications. Twenty questions are completed by the patient/caregiver. Item-specific instructions and an appendix of complementary additional scales are provided. Movement disorder specialists and study coordinators administered the UPDRS (55 items) and MDS-UPDRS (65 items) to 877 English speaking (78% non-Latino Caucasian) patients with Parkinson's disease from 39 sites. We compared the two scales using correlative techniques and factor analysis. The MDS-UPDRS showed high internal consistency (Cronbach's alpha = 0.79-0.93 across parts) and correlated with the original UPDRS (rho = 0.96). MDS-UPDRS across-part correlations ranged from 0.22 to 0.66. Reliable factor structures for each part were obtained (comparative fit index > 0.90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS-UPDRS for rating PD.

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Идентификаторы

DOI: 10.1002/mds.22340

Цитирования и источники

Цитирований: 2Использованных источников: 0

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