Статья

Microfluidic 3D Printing of Emulsion Ink for Engineering Porous Functionally Graded Materials

Martina Marcotulli3D Microfluidic Biofabrication Laboratory Center for Life Nano‐ & Neuro‐ Science – CLN2S Italian Institute of Technology (IIT) Rome 00161 ItalyMaria Celeste TirelliDigital Manufacturing of Biomimetic Systems Laboratory Institute of Physical Chemistry Polish Academy of Sciences Warsaw 01–224 PolandMarina VolpiFaculty of Materials Science and Engineering Warsaw University of Technology Warsaw 02507 PolandJakub JaroszewiczFaculty of Materials Science and Engineering Warsaw University of Technology Warsaw 02507 PolandChiara Scognamiglio3D Microfluidic Biofabrication Laboratory Center for Life Nano‐ & Neuro‐ Science – CLN2S Italian Institute of Technology (IIT) Rome 00161 ItalyPiotr KasprzyckiDepartment of Physical Chemistry of Biological Systems Institute of Physical Chemistry Polish Academy of Sciences Warsaw 01–224 PolandKarol KarnowskiDepartment of Physical Chemistry of Biological Systems Institute of Physical Chemistry Polish Academy of Sciences Warsaw 01–224 PolandWojciech ŚwięszkowskiFaculty of Materials Science and Engineering Warsaw University of Technology Warsaw 02507 PolandGiancarlo Ruocco3D Microfluidic Biofabrication Laboratory Center for Life Nano‐ & Neuro‐ Science – CLN2S Italian Institute of Technology (IIT) Rome 00161 ItalyMarco CostantiniDigital Manufacturing of Biomimetic Systems Laboratory Institute of Physical Chemistry Polish Academy of Sciences Warsaw 01–224 PolandGianluca Cidonio3D Microfluidic Biofabrication Laboratory Center for Life Nano‐ & Neuro‐ Science – CLN2S Italian Institute of Technology (IIT) Rome 00161 ItalyAndrea BarbettaDepartment of Chemistry Sapienza University of Rome Rome 00185 Italy

2022en

ABI

Аннотация

Abstract In the last decade, 3D printing systems have greatly evolved both in terms of processable materials and printing resolutions, becoming a top seed technology for many academic and industrial applications. Nevertheless, manufacturing polymeric materials characterized by a trabecular porosity and functionally graded architecture—where both the local porosity and chemical composition of the matrix change in the 3D space—through additive platforms remains an open technical challenge. In this study, a 3D extrusion printing strategy to tackle this problem is presented. The proposed systems are based on a flow‐focusing microfluidic printing head—to continuously generate oil‐in‐water emulsion inks—and on an agarose fluid–gel used as a temporary support bath for the deposition of the photo‐curable emulsion inks. It is demonstrated that through this strategy one can design a priori and build with high accuracy both discontinuous and continuous functionally graded polymeric foams, where both the density and composition of the materials could be varied independently within arbitrarily complex 3D architectures. This study provides new means for the synthesis of microporous, polymeric FGMs which could find applications ranging from interface tissue engineering to automotive and construction industries.

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Идентификаторы

DOI: 10.1002/admt.202201244

Цитирования и источники

Цитирований: 2Использованных источников: 0

Показатели — AkademScholar