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Insulin pump therapy in type 1 diabetes mellitus: education effectiveness and quality of life

Lyudmila Ibragimovna IbragimovaФГБУ Эндокринологический научный центр, МоскваYury Ivanovich FilippovФГБУ Эндокринологический научный центр, МоскваAlexander Yur'evich MayorovФГБУ Эндокринологический научный центр, Москва
2012en
ABI

Аннотация

Aim. To compare efficacy of special structured program for type 1 diabetes mellitus (DM) group education between users of an integratedreal-time (RT) continuous glucose monitoring (CGM)/continuous subcutaneous insulin infusion (CSII) systems and patientson CSII and self-monitoring of blood glucose (SMBG).Methods. This 4 months trial included 39 adults (18 male, age 27 [24,0;35,0] years) with type 1 DM (duration of diabetes 12[8,0;18,0] years). All subjects were randomized to study groups: 20 in the CSII/SMBG arm and 19 in the RT-CGM/CSII arm. Allparticipants were provided with special structured program for group education of diabetes patients on insulin pump therapy. Qualityof life (QoL) was assessed with questionnaire SF-36. Results. Both groups were not significantly different in HbA1c, BMI and QoL at baseline. After 4 months HbA1c was significantly lowerin both study groups without increase in rate of hypoglycemia. Improvements in QoL were observed in psychic health score in the CSII/SMBG arm and in physical health and psychic health scores in the RT-CGM/CSII arm. There was no significant difference in HbA1c,BMI and QoL between groups. Conclusion. Transfer to CSII during group training under special structured program for patients with type 1 DM significantly improvesglycemic control regardless of glucose monitoring method. Both RT-CGM+CSII and SMBG+CSII amend several aspects of QoL.Finally, transfer to CSII during group training considerably reduces total consumption of trainers time without loss of training quality.

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