Sesquiterpene Coumarins and Related Derivatives from <i>Ferula pallida</i>
Bao‐Ning SuFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanYoshihisa TakaishiFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanGisho HondaFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanMichiho ItoFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanYoshio TakedaFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanOlimjon K. KodzhimatovFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanOzodbek AshurmetovFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Jyosunjima, Tokushima 770, Japan, and Academy of Sciences Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, Uzbekistan
2000en
ABI
Аннотация
Six new compounds-two sesquiterpene coumarins, pallidones A and B (1, 2), and four related derivatives, pallidones C-F (3-6), as well as two known sesquiterpene coumarins, feselol (7) and conferol (8), have been isolated from the EtOAc extracts of the roots of Ferula pallida. All structures of these compounds were determined on the basis of spectral evidence, especially 2D NMR ((1)H-(1)H COSY, HSQC, HMBC, and NOESY) and HRMS. The possible biosynthetic pathway of pallidones C-F (3-6) is discussed.
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