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Is otitis media with effusion a biofilm infection?

N. FergieDepartment of Otolaryngology and Head and Neck Surgery, Queen's Medical Centre, Nottingham, UK. [email protected]Roger BaystonBiomaterials-related Infection Group, School of Medical and Surgical Sciences, University of Nottingham, Nottingham andJeffrey P. PearsonDepartment of Physiology, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, UKJohn P. BirchallDepartment of Otolaryngology and Head and Neck Surgery, Queen's Medical Centre, Nottingham,
2004en
ABI

Аннотация

Recent attention has focused on the possibility that otitis media with effusion (OME) may represent a chronic infective state such as those evidenced in conditions secondary to biofilms or small colony variants. This review discusses the evidence suggesting that this may indeed be the case and explains why this may prove to be important in the future management of this condition by discussing recent advances in understanding these bacterial phenotypic variants.

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