In Vitro Antioxidant, Antimicrobial, and Antiviral Activities of the Essential Oil and Various Extracts from Herbal Parts and Callus Cultures of <i>Origanum acutidens</i>
Münevver SökmenDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchJulia SerkedjievaDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchDimitra DafereraDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchMedine GüllüceDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchMoschos G. PolissiouDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchBektaş TepeDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchH. Aşkın AkpulatDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchFikrettin Şahi̇nDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and ResearchAtalay SökmenDepartment of Chemistry, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; Institue of Microbiology, Bulgarian Academy of Science, Sofia, Bulgaria; Laboratory of General Chemistry, Agricultural University of Athens, Iera Odos 75, Athens 118 55, Greece; Department of Biology, Faculty of Art and Science, Atatürk University, Erzurum 25240, Turkey; Department of Biology, Faculty of Art and Science, Cumhuriyet University, 58 140 Sıvas, Turkey; and Biotechnology Application and Research
2004en
ABI
Аннотация
The essential oil and various extracts obtained from Origanum acutidens and methanol extracts (MeOH) from callus cultures have been evaluated for their antioxidative, antimicrobial, and antiviral properties. The essential oil exhibited strong antimicrobial activity with a significant inhibitory effect against 27 (77%) of the 35 bacteria, 12 (67%) of the 18 fungi, and a yeast tested and moderate antioxidative capacity in DPPH and beta-carotene/linoleic acid assays. GC and GC-MS analyses of the oil resulted in the identification of 38 constituents, carvacrol being the main component. The MeOH extracts obtained from herbal parts showed better antioxidative effect than that of butylated hydroxytoluene (BHT), whereas callus cultures also exhibited interesting antioxidative patterns. Concerning antiviral activity, none of the extracts inhibited the reproduction of influenza A/Aichi virus in MDCK cells. The MeOH extracts from herbal parts inhibited the reproduction of HSV-1, and also callus cultures exerted slight antiherpetic effect.
Перевод пока недоступен
Идентификаторы
Цитирования и источники
Цитирований: 2Использованных источников: 0