Macrocyclic Diterpene Polyesters of the Jatrophane Type from <i>Euphorbia esula</i>
Judit HohmannDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, HungaryAndrea VasasDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, HungaryGábor GüntherDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, HungaryImre MáthéDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, HungaryFerenc EvanicsDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, HungaryGyörgy DombiDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, HungaryGyula JerkovichDepartment of Pharmacognosy, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, Department of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University, P.O. Box 121, H-6701 Szeged, Hungary, and Spectroscopic Department, Institute for Drug Research Ltd., P.O. Box 82, H-1325 Budapest, Hungary
1997en
ABI
Аннотация
Three new jatrophane diterpenes, esulatin A, B and C (1-3) were isolated and characterized from the whole, undried plant of Euphorbia esula. By means of spectral analysis, the structures were established as penta- and heptaesters of hitherto unknown, polyfunctional diterpene parent alcohols. Esulatin A (1) and C (3) are the diterpenoids with the highest degree of esterification identified to date from the family Euphorbiaceae.
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