Статья

Tough adhesives for diverse wet surfaces

Jianyu LiDepartment of Mechanical Engineering, McGill University, Montreal, Quebec H3A 0G4, CanadaAdam D. CelizAdvanced Materials and Healthcare Technologies Division, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UKJiawei YangJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USAQuansan YangJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USAIsaac WamalaDepartments of Cardiac Surgery, Boston Children’s Hospital, Boston, MA 02115, USAWilliam WhyteAdvanced Materials and Bioengineering Research Centre, Royal College of Surgeons in Ireland and Trinity College Dublin, Dublin, IrelandBo Ri SeoJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USANikolay V. VasilyevDepartments of Cardiac Surgery, Boston Children’s Hospital, Boston, MA 02115, USAJoost J. VlassakJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USAZhigang SuoJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USADavid MooneyJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA

2017en

ABI

Аннотация

Adhesion to wet and dynamic surfaces, including biological tissues, is important in many fields but has proven to be extremely challenging. Existing adhesives are cytotoxic, adhere weakly to tissues, or cannot be used in wet environments. We report a bioinspired design for adhesives consisting of two layers: an adhesive surface and a dissipative matrix. The former adheres to the substrate by electrostatic interactions, covalent bonds, and physical interpenetration. The latter amplifies energy dissipation through hysteresis. The two layers synergistically lead to higher adhesion energies on wet surfaces as compared with those of existing adhesives. Adhesion occurs within minutes, independent of blood exposure and compatible with in vivo dynamic movements. This family of adhesives may be useful in many areas of application, including tissue adhesives, wound dressings, and tissue repair.

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Идентификаторы

DOI: 10.1126/science.aah6362

Цитирования и источники

Цитирований: 2Использованных источников: 0

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