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Cyclic olefin copolymer with noble metal nanostructures as antibacterial material

Petr SlepickaDepartment of Solid State Engineering, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague, The Czech RepublicJonáš PriškinDepartment of Solid State Engineering, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague, The Czech RepublicBára FrýdlováDepartment of Solid State Engineering, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague, The Czech RepublicPetr SajdlDepartment of Power Engineering, University of Chemistry and Technology Prague, 166 28 Prague, Czech RepublicVaclav SvorcikDepartment of Solid State Engineering, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague, The Czech RepublicAnna KutováInstitute of Physics of the Czech Academy of Sciences Na Slovance 1999/2, 182 00 Prague 8Petr MalinskýNeutron Physics Department of Nuclear Physics Institute CAS, Hlavní 130, 250 68 Husinec-ŘežZdeněk HrdličkaDepartment of Polymers, The University of Chemistry and Technology Prague, 166 28 Prague, Czech RepublicOndřej KvítekDepartment of Solid State Engineering, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague, The Czech RepublicNikola Slepičková KasálkováDepartment of Solid State Engineering, University of Chemistry and Technology Prague, Technická 3, 166 28 Prague, The Czech Republic

Zenodo (CERN European Organization for Nuclear Research)repository2026

ABI

Аннотация

Abstract of the work: The work is aimed on the application of the solvent casting method of cyclic olefin copolymer TOPAS® for the preparation of thin films. Noble metal nanostructures deposited on cyclic olefin copolymer (COC) substrates offer a versatile platform for advanced applications due to their unique optical, catalytic, and biocompatible properties. The integration of nanostructures with COC combines excellent chemical resistance, optical transparency, and ease of microfabrication with the plasmonic and catalytic functionality of noble metals. Such hybrid systems are promising for use in biosensing, photonic devices, and surface-enhanced spectroscopies. The COC films have been modified by argon plasma and subsequently sputtered with noble metals. After thermal and laser modification, Au films show antibacterial properties against gram-negative Escherichia coli and Ag layers act bactericidally for both gram-negative Escherichia coli and gram-positive Staphylococcus aureus. Samples were examined by AFM, DSC, RBS, SEM and TGA during preparation and their roughness and water wettability was determined. The results point to a functional modification of the pharmaceutical packaging material used so far, which in connection with the expanding resistance of bacteria to antibiotic treatment is a promising path for material development.

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Идентификаторы

DOI: 10.5281/zenodo.19003187

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