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An overview on nanoparticle-based strategies to fight viral infections with a focus on COVID-19

Saman YasaminehDepartment of Medical Biotechnology, Institute of Higher Education Rab-Rashid, Tabriz, IranHesam Ghafouri KalajahiDepartment of Biotechnology, Institute of Science, Uskudar University, Istanbul, TurkeyPooneh YasaminehYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, IranYalda YazdaniImmunology Research Center, Tabriz University of Medical Sciences, Tabriz, IranOmid GholizadehDepartment of Virology, Faculty of Medical Sciences, Tabriz University of Medical Sciences, Tabriz, IranRaheleh TabatabaieDepartment of Medical Immunology, Faculty of Medical Sciences, Hamadan University, Hamadan, IranHamed AfkhamiDepartment of Medical Microbiology, Faculty of Medicine, Shahed University of Medical Science, Tehran, IranFatemeh DavodabadiDepartment of Biology, Faculty of Basic Science, Payame Noor University, Tehran, IranAlireza Khanalipour farkhadYoung Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, IranDaryoush PahlevanDeterminants of Health Research Center, Semnan University of Medical Sciences, Semnan, IranAkram Firouzi‐AmandiDepartment of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranKazem Nejati‐KoshkiPharmaceutical Sciences Research Center, Ardabil University of Medical Sciences, Ardabil, Iran. [email protected]Mehdi DadashpourCancer Research Center, Semnan University of Medical Sciences, Semnan, Iran. [email protected]
2022en
ABI

Аннотация

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to COVID-19 and has become a pandemic worldwide with mortality of millions. Nanotechnology can be used to deliver antiviral medicines or other types of viral reproduction-inhibiting medications. At various steps of viral infection, nanotechnology could suggest practical solutions for usage in the fight against viral infection. Nanotechnology-based approaches can help in the fight against SARS-CoV-2 infection. Nanoparticles can play an essential role in progressing SARS-CoV-2 treatment and vaccine production in efficacy and safety. Nanocarriers have increased the speed of vaccine development and the efficiency of vaccines. As a result, the increased investigation into nanoparticles as nano-delivery systems and nanotherapeutics in viral infection, and the development of new and effective methods are essential for inhibiting SARS-CoV-2 infection. In this article, we compare the attributes of several nanoparticles and evaluate their capability to create novel vaccines and treatment methods against different types of viral diseases, especially the SARS-CoV-2 disease.

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