Role of IL-10 in the progression of kidney disease
Inna SinuaniInna Sinuani, Judith Sandbank, Pathology Department, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, 70300, IsraelIlia BeberashviliInna Sinuani, Judith Sandbank, Pathology Department, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, 70300, IsraelZhan AverbukhInna Sinuani, Judith Sandbank, Pathology Department, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, 70300, IsraelJudith SandbankInna Sinuani, Judith Sandbank, Pathology Department, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, 70300, Israel
2013en
ABI
Аннотация
Interleukin-10 (IL-10), a cytokine with anti-inflammatory and immunomodulatory functions, regulates the biology of B and T cells. The present review describes the role of IL-10 in normal renal physiology, during acute kidney injury and in the development of chronic renal failure. We further discuss IL-10-induced cellular and molecular pathways and their link to the progression of kidney injury.
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