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111indium bone marrow scintigraphy as an aid in selecting marrow biopsy sites for the evaluation of marrow elements in patients with lymphoma

Edward H. GilbertFellow, Division of Radiation Therapy, Department of RadiologyJohn D. EarleDivision of Nuclear Medicine and the Paul A. Bissinger Memorial Center for Radiation Therapy, Department of Radiology, Stanford University Medical Center, Stanford, CaliforniaEli GlatsteinAssistant Professor, Division of Radiation Therapy, Department of RadiologyMichael L. GorisAssistant Professor, Division of Nuclear Medicine, Department of RadiologyHenry S. KaplanDivision of Nuclear Medicine and the Paul A. Bissinger Memorial Center for Radiation Therapy, Department of Radiology, Stanford University Medical Center, Stanford, CaliforniaJoseph P. KrissProfessor, Division of Nuclear Medicine, Department of Radiology
1976en
ABI

Аннотация

One hundred and two previously treated lymphoma patients were studied with 111Indium bone marrow scans and bone marrow biopsies. The biopsies were considered to represent sampling errors when the cellularity of the biopsy did not reflect the general state of the marrow organ cellularity as demonstrated by the scan. In each instance the accuracy of the scan was confirmed by either another biopsy or the subsequent clinical course of the patient. Sampling errors were infrequent (1/51) in patients with normal peripheral blood counts and whose marrow had never been involved with tumor. Errors were especially likely (17/51) in patients who had had marrow involvement or those who had anemia, leukopenia, or thrombocytopenia. The 111Indium bone marrow scan allows the clinician to avoid selecting a biopsy site with a high risk for sampling error.

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