Мақола

High Genetic Diversity of Measles Virus, World Health Organization European Region, 2005–2006

Jacques R. KremerKevin BrownLi JinSabine SantibanezSergey V. ShulgaYair AboudyIsrael Ministry of Health, Tel Hashomer, IsraelIrina V. DemchyshynaMinistry of Health, Kyiv, UkraineSultana DjemilevaMinistry of Public Health of the Republic of Uzbekistan, Tashkent, UzbekistanJuan E. Echevarrı́aInstituto de Salud Carlos III, Majadahonda, SpainDavid F. FeatherstoneWHO, Geneva, SwitzerlandMirsada HukićUniversity of Sarajevo, Sarajevo, Bosnia and HerzegovinaKari JohansenSwedish Institute for Infectious Disease Control, Solna, SwedenB LitwińskaState Institute of Hygiene, Warsaw, PolandElena N. LoparevaCenters for Disease Control and Prevention, Atlanta, Georgia, USAEmilia LupulescuNational Institute for Research and Development in Microbiology and Immunology “Cantacuzino,” Bucharest, RomaniaΑndreas MentisInstitut Pasteur Hellenique, Athens, GreeceZefira MihnevaNational Centre of Infectious and Parasitic Diseases, Sofia, BulgariaMaría Mar MosqueraInstituto de Salud Carlos III, Majadahonda, SpainMark MuscatStatens Serum Institute, Copenhagen, DenmarkNaumova MaJasminka NedeljkovićInstitute of Virology, Vaccine and Sera Torlak, Belgrade, SerbiaLjubov S. NekrasovaMinistry of Health, Kyiv, UkraineFabio MaguranoIstituto Superiore di Sanità, Rome, ItalyClaudia FortunaIstituto Superiore di Sanità, Rome, ItalyHelena Rebelo‐de‐AndradeInstituto Nacional de Saúde Dr. Ricardo Jorge, Lisboa, PortugalJean‐Luc RichardSwiss Federal Office of Public Health, Berne, SwitzerlandAlma RoboInstitute of Public Health, Tirana, AlbaniaPaul A. RotaCenters for Disease Control and Prevention, Atlanta, Georgia, USAElena SamoilovichMinistry of Health, Minsk, BelarusInna SarvГ. В. СемейкоMinistry of Health, Minsk, BelarusNazim ShugayevMinistry of Health, Baku, AzerbaijanElmira UtegenovaMinistry of Health, Almaty, Republic of KazakhstanRob van BinnendijkRijksinstituut voor Volksgezondheid en Milieu, Bilthoven, the NetherlandsLasse VinnerStatens Serum Institute, Copenhagen, DenmarkDiane Waku‐KouomouINSERM U404, Lyon, FranceThorsten WildINSERM U404, Lyon, FranceDavid BrownAnnette MankertzClaude P. MullerMick N. MuldersState Institute of Hygiene, Warsaw, PolandWHO Regional Office for Europe, Copenhagen, Denmark

Emerging infectious diseasesjournal2008en

ABI

Аннотация

During 2005-2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities.

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Мавзулар

Virology and Viral Diseases Respiratory viral infections research Immunodeficiency and Autoimmune Disorders

Идентификаторлар

DOI: 10.3201/eid1401.070778

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