Efficiency of nebulised therapy in preventive maintenance of bronchial stump insufficiency after pneumonectomy

Introduction: Introduction for preventive maintenance COPD nebulised therapy (NT) promotes the high local activity of inhalated remedies. Purpose: To value efficiency of NT in preventive maintenance of bronchial stump insufficiency (BSI) after pneumonectomy (PE). Material and methods: The interesting results were received at study of the influence accompanying pathology on frequency of development BSI after PE. The frequent diseases were COPD and heart-vascular pathology. So from 390 patients in 207 (53,1%) accompanying COPD was revealled, on background which after PE in 36 (17,4%) patients was noted development of BSI. In turn, amongst 183 (46,9%) patients without accompanying COPD this complication was noted only in 2,7% of the cases. That is to say, presence of COPD raised the risk of the development BSI more then in 6 once. Results: Introduction NT has allowed in the main group to reduce the risk of the intensification COPD to 16,1% after PE on the left and 17,2% after PE on the right, and frequency of the development of BSI on background accompanying COPD decreased to 3,2% and 6,9% accordingly. In the main group accompanying COPD was revealled in 60 patients (61,2%), activation after operation was noted in 10 (16,7%) patients, but development of BSI only in 3 patients, that has formed 5,0%. Findings: Introduction of NT for preventive maintenance COPD promotes not only reliable improvement of the factors of breathing frequency (P<0,002) and functional respiratory tests (P<0,001), but also reduction of the frequency of the intensification of obstructive syndrome from 52,4% to 16,7% that led to reduction of the risk of development BSI from 16,5% to 5,0%.

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