914 Clinical Features of Mycoplasmal Pneumonia at Early Age Children
Аннотация
<h3>Background and Aims</h3> In recent years the problem of mycoplasmal pneumonia, especially in early age children attracted the attention of pediatricians around the world. Purpose - to study the peculiarities of clinical course of mycoplasmal pneumonia in early age children. <h3>Methods</h3> From 2009 to 2011 among children with pneumonia analyzed for the presence of mycoplasmal pneumoniae. The study involve 450 children aged 5 months to 3 years. Antibodies to Mycoplasma pneumoniae were detected by ELISA in 60 children. Raising antibodies indicated more than 4 times. Conducted clinical observations, X-ray methods, the method of ELISA for the detection of IgM antibodies to Mycoplasma pneumoniae, DNA display M. pneumoniae in sputum by PCR. <h3>Results</h3> Mycoplasmal pneumonia began sharply at 80% of children with high fever, cough was dry and unproductive. Outpatient treatment starting antibiotics penicillin group did not give the effect. Pyrexia over 38°C was observed in 95% of children. On radiographic studies, the bilateral homogeneous lobular infiltration revealed in the lungs at the majority of children (75%). Segmental nature of the infiltrative changes detected in 5% right-sided focal character pneumonic process occurred in 20%, left-side lung had 9.5% of children. In the analysis of peripheral blood revealed anemia in 25% of children, moderate leukocytosis in 89%, marked lymphocytosis (95%) and accelerated erythrocyte sedimentation rate (89%). <h3>Conclusion</h3> For early age children with mycoplasmal pneumonia is characterized by severe intoxication, prolonged dry cough. On the radiograph indicated bilateral focal mainly infiltration. In the hemogram - a moderate leukocytosis, lymphocytosis, ESR acceleration.