Opinion to: Design, Synthesis, Antimicrobial, and Antioxidant Activities of Novel {4,5-(substituted diphenyl)-4H-1,2,4-triazol-3-ylthio}acetyl Chloride

To discover novel triazole-based antimicrobial agents, design and synthesis of acid chlorides possessing a 1,2,4-triazole core was reported in this journal in 2018. However, we found that the reported spectroscopic data did not show any agreement with the proposed acid chloride structure. Herein, we described our opinion, which was supported by IR data, circumstantial evidences, and mechanistic insight, that the products obtained in the topical paper would be thioesters.

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