Lehmanniaside, a new cycloartane triterpene glycoside from <i>Astragalus lehmannianus</i>
М. А. АгзамоваInstitute of the Chemistry of Plant Substances, Academy Sciences of Uzbekistan, Tashkent, UzbekistanNilufar Z. MamadalievaDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), GermanyAndrea PorzelDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), GermanyHidayat HussainDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), GermanyMthandazo DubeDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), GermanyKatrin FrankeDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), GermanyAbdulaziz A. JanibekovInstitute of the Chemistry of Plant Substances, Academy Sciences of Uzbekistan, Tashkent, UzbekistanLudger A. WessjohannDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany
ABI
Аннотация
Chemical investigation of the aerial parts of Astragalus lehmannianus Bunge (Leguminosae) led to the isolation and identification of a new cycloartane triterpene glycoside – lehmanniaside (2'-O-acetyl-3-β-O-D-xylopyranosyl-3β,6α,16β,24α-tetrahydroxy-20,25-epoxycycloartane). Its structure was elucidated by means of spectroscopic analysis (HR-MS, 1D and 2D NMR). Bioassays showed that lehmanniaside exhibits weak anthelmintic, antifungal, and cytotoxic activities.
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