PATHOMORPHOLOGICAL CHANGES IN CEREBRAL VASCULATURE IN ISCHAEMIC STROKE

The article is devoted to the pathomorphological features of ischemic brain strokes. The aim of the investigation was to establish the morphological peculiarities of the cerebral microcirculatory stroke development. The analysis of 48 cases was carried out, in which an acute cerebral circulation disorder was diagnosed. It was found that at cerebral artery ischemia in the brain tissue in the early period after ischemia initially develops discirculatory and edematous phenomena, then begins the predominance of destructive-necrotic changes in both neural and glial cells. To these destructive changes in the focus of acute ischaemia, an inflammatory-regenerative response develops in the form of vasodilation, migration of leucocytes from the blood to the focus of destruction, and formation of an inflammatory-cell demarcation ramp around the necrosis.

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