The effectiveness of the treatment of heart failure metabolic syndrome on the parameters of post infarct remodeling and functional state of the left ventricle in patients with metabolic syndrome

This paper examined the anti-remodeling efficacy of complex pharmacotherapy in the presence of LV diastolic dysfunction in CHF with the use of perindopril, bisoprolol and verospiron in patients with MS. To achieve the set objectives, 197 male patients with chronic heart failure (CHF) of ischemic genesis II-III functional class (FC) according to NYHA, aged 40-60 years old with a history of myocardial infarction from 6 months, were examined within 5 years. Verification of the diagnosis was carried out based on the classification of the New York Heart Association (NYHA), the six-minute walk test (TSH) and on the clinical assessment scale (SHOKS). The average TShH indicator was 304.2 ± 22.13m (261-349m). According to the classification of CHF (ESC 2016), depending on the level of ejection fraction (EF), all examined patients with CHF were also subdivided into subgroups: with normal (preserved EF) - EF ≥50% (HFpEF) and intermediate EF (gray zone) - EF = 40-49% (HFmrEF). Depending on the presence of MS components, 3 groups of patients were identified: Group I (n = 70), patients without MS (CHF FC II -38, CHF FC III - 32 patients

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