Significant Pathogenetic Factors in the Development of Chronic Heart Failure with Preserved Ejection Fraction

Chronic heart failure (CHF), being an outcome of cardiovascular continuum, leads to worsening of the course of not only the causes of the disease, but also to its decompensation, rehospitalizations, which leads to difficulties in the care of these patients and becomes a socio-economic problem. The prevalence of CHF in Western countries ranges from 1% to 2% in the general population, reaching 10% in those over 70 years of age. In the Russian Federation, the EPOHA study data show an incidence of CHF of 7-10%. In Uzbekistan, CHF is also one of the leading complications of cardiovascular disease (CVD). The presence of strict diagnostic positioning criteria increases the number of patients with CHF III-IV, and the use of softer criteria sharply expands the population of patients with CHF I-II.

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