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Gestational diabetes Mellitus and sex hormone-binding globulin.

Iroda TojievaRepublican Specialized Scientific and Practical Medical Center of Endocrinology named after Y.Kh. Turakulova, Tashkent, UzbekistanFeruza KhaydarovaRepublican Specialized Scientific and Practical Medical Center of Endocrinology named after Y.Kh. Turakulova, Tashkent, Uzbekistan
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 GDM is defined as impaired glucose tolerance of variable severity with first onset during pregnancy. The common mechanism in gestational diabetes mellitus is the beta cell dysfunction, due to the antagonism created by the anti-insulin hormones in pregnancy. The sex hormone-binding globulin (SHBG), a protein closely linked to insulin and insulin resistance.

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