The Main Complications in Patients with Acute Leukemia during the Period of Myelotoxic Agranulocytosis

Annotation: Improvement of chemotherapeutic protocols and algorithms of accompanying treatment made it possible to increase the survival rate of patients with tumors of the blood system. Despite these advances, most of the cytostatic drugs currently widely used to treat patients with hemoblastosis, in addition to the antitumor effect, also cause myelosuppression and the development of granulocytopenia. Granulocytopenia is one of the main factors associated with infectious complications in patients with tumors of the blood system. The nature of infectious complications may differ depending on the duration of granulocytopenia. Keywords: agranulocytosis, immune agranulocytosis, myelotoxic agranulocytosis, acute lymphoblastic leukemias, level of persuasion of recommendations.

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