EFFECTS OF L - CARNITINE ON SYSTEMIC INFLAMMATION AND OXIDATIVE STRESS IN COVID-19 PATIENTS

Abstract. Over the past decade, it has become apparent that the inflammatory process, characterized by the activation and proliferation of endothelial and smooth muscle cells with the formation of a large number of pro-inflammatory mediators, plays an important role. The systemic inflammatory response, or acute phase response, is currently considered one of the most significant mechanisms of the pathogenesis of COVID-19 and its complications [1,2].\n\n\nAmong the wide range of biological and immunological markers used in clinical practice to assess the activity of inflammation, special importance is attached to CRP, which is a protein of the acute phase of inflammation [3-4]. In connection with the pandemic of coronavirus infection, there have been discussions recently about the role of antioxidants on indicators of systemic inflammation and oxidative stress in patients with COVID-19.

Ҳали таржима қилинмаган