Evaluation of the Effect on the Nervous System of Substances with an Alkaloid Structure Having Antitumor Activity
Yu. R. MirzaevCandidate of Medical Sciences, senior scientific Researcher at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of UzbekistanTolmas Tolibovich KhamroevBasic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of UzbekistanE. M. RuzimovJunior scientific Researcher at the S.Y. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of UzbekistanB. N. KhandamovBasic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of UzbekistanSh. M. AdizovPhD, Senior scientific Researcher at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan
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Аннотация
Indole alkaloids including sedative activity of pyrazolone iodine methylate and pyrazolone chloride were caused by alcohol sleep and feeling against arousal or fear effects were studied by the Sonberg method. In this study, pyrazoline iodine methylate and pyrazaline chloride reduced sleep time by increasing the sleep time caused by alcohol, in the Sonberg method, the excretion of urine and excrement by experimental animals decreased due to noise and external factors. This indicates that the studied substances have a calming effect.
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