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EVALUATION OF PRODROMAL STAGE BIOMARKERS IN PARKINSON'S DISEASE AND THEIR ROLE IN DISEASE PROGRESSION USE OF MODERN DIGITAL TECHNOLOGIES

Khilola Maratovna DaminovaDepartment of Nervous Diseases and Medical Psychology, Tashkent Medical Academy, UzbekistanR. MatmurodovDepartment of Nervous Diseases and Medical Psychology, Tashkent Medical Academy, UzbekistanD. AkramovaDepartment of Nervous Diseases and Medical Psychology, Tashkent Medical Academy, UzbekistanGulhayo KhamdamovaDepartment of Nervous Diseases and Medical Psychology, Bukhara State Medical Institute, UzbekistanGulizahro TurayevaDepartment of Nervous Diseases and Medical Psychology, Gulistan State University, UzbekistanMadina AbdullayevaDepartment of Nervous Diseases and Medical Psychology, Tashkent State University of Economics, UzbekistanBobur Batirovich ValiyevDepartment of Finance, International Islamic Academy, UzbekistanZokir Rustamovich SodiqovDepartment of Finance, International Islamic Academy, UzbekistanAnvar Aidjonovich HudoyorovDepartment of Finance, International Islamic Academy, UzbekistanNasrulla Tashmuratovich TilabovDepartment of Finance, Tashkent State University of Economics, Uzbekistan
2022en
ABI

Аннотация

The article presents the results of observation of 213 patients with PD, including 90 (42.25%) women, 123 (57.75%) men, whose mean age was 46.17±0.63 years. Patients with PD were selected in accordance with the international criteria of the British brain bank "Parkinson's Disease Society Brain Bank". Patients underwent CT or MRI of the brain. Olfactory disturbances were studied using the Sniffin Stix Test (SST) by Burchard (Hamburg, Germany). All patients underwent examination of the ENT organs. The results obtained indicate that the presence of hyposmia in patients with early onset of PD is an important biomarker of the latent neurodegenerative process of the “Parkinsonian” type and, therefore, the risk of future development of PD.

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