DETERMINATION OF THE MECHANISM OF HEMOSTATIC ACTION OF GEPROCELL IN AN EXPERIMENTAL MODEL OF HEAT INJURY

In case of long-term non-healing wounds the skin defect persists for a long time, significant cicatricial and dystrophic changes occur in the surrounding tissues, there is no tendency for stable independent epithelialization. Therefore, surgical treatment of long-lasting wounds that do not heal has taken the leading place in pathogenetic therapy, and it is primarily autodermoplasty. Any wound with a diameter of more than 5 cm needs to be covered artificially with a flap or skin slices to achieve a lasting therapeutic effect and a good functional result. A wound can be closed with local tissue grafting: excision of the edges and the bottom of the wound, mobilisation of the edges and a dummy suture. In some cases the skin can be mobilised by means of a loosening incision. The wound can also be closed by applying secondary sutures with excision of the edges and the wound bed (late secondary suture).

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