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ABOUT HBV DNA REPLICATION IN HEPATOCYTES DURING HBV AND HDV CO-INFECTION

Dalimov T.K.,Republican Specialized Scientific and Practical Medical Center of Epidemiology, Microbiology, Infectious and Parasitic Diseases, Ministry of Health of the Republic of UzbekistanMirrakhimova N.MRepublican Specialized Scientific and Practical Medical Center of Epidemiology, Microbiology, Infectious and Parasitic Diseases, Ministry of Health of the Republic of UzbekistanTuichiev L.N.,Republican Specialized Scientific and Practical Medical Center of Epidemiology, Microbiology, Infectious and Parasitic Diseases, Ministry of Health of the Republic of UzbekistanMustafakulova A.H.Republican Specialized Scientific and Practical Medical Center of Epidemiology, Microbiology, Infectious and Parasitic Diseases, Ministry of Health of the Republic of Uzbekistan
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Abstract. The article discusses the replication of HBV DNA in hepatocytes when the patients catch HBV and HDV co-infection. We tried to study the molecular interactions of HDV and HBV viruses as many aspects of the pathogenesis of Delta hepatitis remain undiscovered. Different experiments by several scientists were reviewed, and on the basis of shortfalls, we decided to examine patients with HCVD, in whom HBV DNA was not detected in the blood during PCR examination.

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