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EFFECTS OF THE METABOLIC SYNDROME ON THE LEVEL OF PRO-INFLAMMATORY CYTOKINES (IL-1β AND IL-6) IN PATIENTS WITH OSTEOARTHRITIS

N.A.RamazanovaTashkent Medical Academy Tashkent, UzbekistanN. DadabaevaTashkent Medical Academy Tashkent, UzbekistanH.T.MiraxmedovaTashkent Medical Academy Tashkent, UzbekistanG.B.SaidrasulovaTashkent Medical Academy Tashkent, Uzbekistan
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Abstract: This article summarizes the current understanding of the role of cytokines in the pathogenesis of osteoarthritis (OA). An imbalance between pro-inflammatory and anti-inflammatory cytokines in the joint tissues contributes to the development of inflammation and cartilage damage, which leads to progressive joint degeneration. This research studied the role of pro-inflammatory cytokines in OA and the impact on the course of disease against the background of metabolic syndrome.

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