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Involvement of sphingolipids in the cell metabolism and various pathologies

Saatov T.S.Institute of biophysics and biochemistry under Mirzo Ulugbek National University of Uzbekistan, Uzbekistan Ministry of Higher EducationIrgasheva S.U.,Institute of biophysics and biochemistry under Mirzo Ulugbek National University of Uzbekistan, Uzbekistan Ministry of Higher EducationIbragimova E.A.Institute of biophysics and biochemistry under Mirzo Ulugbek National University of Uzbekistan, Uzbekistan Ministry of Higher Education
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Abstract. Being an essential component of plasma membrane, sphingolipids are bioactive lipids playing key roles in regulation of signaling. Compositions of sphingolipids, sphingolipid metabolism and its regulation in tissues, as well as involvement of sphingolipids in various pathological processes are analyzed in the review.

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