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Иш: CRISPR-Cas9-Based Technology and Its Relevance to Gene Editing in Parkinson’s Disease

  1. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

    Martin Jínek, Krzysztof Chylinski, Ines Fonfara +3

    Мақола20127 иқтибос
    ABI

  2. Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

    Valery L. Feigin, Amanuel Alemu Abajobir, Kalkidan Hassen Abate +97

    Мақола20175 иқтибос
    ABI

  3. Multiplex Genome Engineering Using CRISPR/Cas Systems

    Le Cong, F. Ann Ran, David Cox +8

    Мақола20134 иқтибос
    ABI

  4. CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

    Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau +5

    Мақола20074 иқтибос
    ABI

  5. Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

    Kira S. Makarova, Yuri I. Wolf, Jaime Iranzo +23

    Шарҳ мақола20194 иқтибос
    ABI

  6. Parkinson's disease

    Bastiaan R. Bloem, Michael S. Okun, Christine Klein

    Шарҳ мақола20214 иқтибос
    ABI

  7. One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

    Haoyi Wang, Hui Yang, Chikdu Shivalila +4

    Мақола20133 иқтибос
    ABI

  8. Incidence of Parkinson's Disease: Variation by Age, Gender, and Race/Ethnicity

    Stephen K. Van Den Eeden

    Мақола20033 иқтибос
    ABI

  9. 53BP1, BRCA1, and the Choice between Recombination and End Joining at DNA Double-Strand Breaks

    James M. Daley, Patrick Sung

    Шарҳ мақола20143 иқтибос
    ABI

  10. Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

    Yoshizumi Ishino, Hideo Shinagawa, K Makino +2

    Мақола19873 иқтибос
    ABI

  11. Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

    Lei S. Qi, Matthew H. Larson, Luke A. Gilbert +4

    Мақола20133 иқтибос
    ABI

  12. Delivering CRISPR: a review of the challenges and approaches

    Christopher A. Lino, Jason C. Harper, James P. Carney +1

    Шарҳ мақола20183 иқтибос
    ABI

  13. DNA targeting specificity of RNA-guided Cas9 nucleases

    Patrick D. Hsu, David A. Scott, Joshua A. Weinstein +11

    Мақола20132 иқтибос
    ABI

  14. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

    Elitza Deltcheva, Krzysztof Chylinski, Cynthia M. Sharma +6

    Мақола20112 иқтибос
    ABI

  15. A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes

    Daniel H. Haft, Jeremy Selengut, Emmanuel F. Mongodin +1

    Мақола20052 иқтибос
    ABI

  16. Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

    Taeyoung Koo, Jungjoon Lee, Jin‐Soo Kim

    Шарҳ мақола20152 иқтибос
    ABI

  17. Genome engineering using the CRISPR-Cas9 system

    F. Ann Ran, Patrick D. Hsu, Jason Wright +3

    Мақола20132 иқтибос
    ABI

  18. Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial

    Kevin Fitzgerald, Maria Frank-Kamenetsky, Svetlana Shulga‐Morskaya +17

    Мақола20132 иқтибос
    ABI

  19. RNA-Guided Human Genome Engineering via Cas9

    Prashant Mali, Luhan Yang, Kevin M. Esvelt +5

    Мақола20132 иқтибос
    ABI

  20. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

    Yanfang Fu, Jennifer A Foden, Cyd Khayter +4

    Мақола20132 иқтибос
    ABI

  21. Electrospun biomimetic nanocomposite nanofibers of hydroxyapatite/chitosan for bone tissue engineering

    Yanzhong Zhang, Jayarama Reddy Venugopal, A El-Turki +3

    Мақола20082 иқтибос
    ABI

  22. The blood-brain barrier: Bottleneck in brain drug development

    William M. Pardridge

    Шарҳ мақола20042 иқтибос
    ABI

  23. Viral vectors: a look back and ahead on gene transfer technology.

    Laura Vannucci, Michele Lai, Flavia Chiuppesi +2

    Мақола20132 иқтибос
    ABI

  24. Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

    Daniel G. Healy, Mario Falchi, Sean S. O’Sullivan +22

    Мақола20082 иқтибос
    ABI

  25. Parkinson's disease: clinical features and diagnosis

    Joseph Jankovic

    Шарҳ мақола20082 иқтибос
    ABI