Data From Foreign Literature on The Morphofunctional Properties of Lymphoid Cells Of The Spleen

The spleen is an excellent lymphoid organ that harmoniously combines innate and adaptive immunity, helping to strictly remove blood-borne microorganisms and old erythrocytes from circulation. The functions of the spleen are focused on systemic circulation. Thus, it does not have afferent lymphatic vessels. It consists of two functionally and morphologically distinct sections: red pulp and white pulp. Red pulp is a blood filter that removes foreign substances and damaged and effete erythrocytes. It is also a storage site for iron, erythrocytes and platelets. As an example, it is the site of hematopoiesis in rodents, especially in the fetus and neonatal animals. The spleen is also the largest secondary lymphoid organ containing a quarter of the body's lymphocytes, initiating immune reactions against blood-borne antigens. This function is loaded into the white pulp that surrounds the central arterioles. The white pulp consists of three lower parts: the periarteriolar lymphoid shell (PALS), the follicles and the marginal zone.

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