COMPARATIVE ASSESSMENT OF THE STRUCTURAL AND FUNCTIONAL PARAMETERS OF THE OPTIC NERVE IN COMPLEX NEUROPROTECTIVE TREATMENT

Relevance. Glaucoma is a chronic progressive optic neuropathy with characteristic morphologic changes in the head of optic nerve and progressive death of retinal ganglion fibers with narrowing of the visual field. Thus, a search of a new direction of the drug therapy is needed because of the fact that hypotensive therapy is not completely effective. The most perspective of them is neuroprotection in combination with percutaneous electrostimulation and endonasal electrophoresis that protect neurons of the retina and nerve fibers of optic nerve from different damage factors. Purpose of the study. To assess structural and functional changes in optic nerve after complex neuroprotective treatment in glaucomatous optic neuropathy. Materials and methods. Clinical observation includes 80 (116 eyes) patients with GON aged 42 to 79 years. 45 (56,2%) of them were women, 35 (43,7%) were men, diagnosed with stage II or III POAG and PACG under compensation IOP (21.4±3.1). Results. Analysis of the following observation demonstrate stability of the given functional parameters, that was not noted in the control group where given parameters had comparatively not reliable changes.

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