RHEUMATOID ARTHRITIS TREATED WITH DMARDS AND CARDIOVASCULAR DISEASE RISK

Rheumatoid arthritis (RA) is a disease characterized by joint inflammation and an increased risk of cardiovascular diseases (CVDs). This study examines possible associations between cardiovascular disease and the utilisation of conventional disease-modifying anti-rheumatic drugs (DMARDs) in patients with RA. MTX and SSZ with the latter to lesser extent were associated with a significant reduced risk of CVD than patients with RA who never used either of the drugs or combinations. This study suggests that the use of DMARD, in particular the use of MTX, results in potent suppression of joint inflammation. It also can reduce the development of atherosclerosis and associated CVDs.

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