ROLE OF CYTOKINE STATUS AND ORAL FLUID AND BLOOD ANTIMICROBIAL PEPTIDES IN PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS COMBINED WITH CARDIOVASCULAR DISEASE(literary review)

Generalized periodontitis is not only a focus of chronic infection and a source of sensitization, but also the leading cause of tooth loss (especially in older age groups), leading to serious destructive consequences that disorganize the maxillary system. This fact can seriously affect the quality of human life, making the periodontal problem not only medical, but also social

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