MANCHURIAN SCORPION TISSUES PROTEIN EXTRACTION WITH CHAOTROPIC SOLUTION AND TANDEM ION-EXCHANGE CHROMATOGRAPHY
G. T. MavlonovInstitute of Bioorganic chemistry, Academy of Sciences of Uzbekistan, Tashkent,100125Ahmidin WaliXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1, Urumqi 830011, Xinjiang, P.R. ChinaAmina ArkenXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1, Urumqi 830011, Xinjiang, P.R. ChinaAzimjon A. MAMADRAHIMOVInstitute of Bioorganic chemistry, Academy of Sciences of Uzbekistan, Tashkent,100125Abulimiti YiliXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1, Urumqi 830011, Xinjiang, P.R. ChinaHaji Akber AisaXinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1, Urumqi 830011, Xinjiang, P.R. China
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Аннотация
Manchurian scorpion (Buthus martensii) one of high poisonous types for animals and insects.It represent interest of a wide range of researchers as a source of neurotoxic peptides, potentially useful in medicine, including positive impact at vitiligo by melanin synthesis stimulation.The accelerated-simplified extraction and fractionation of venom gland and other tissues of this scorpion species with subsequent screening of bioactivity on murine melanoma cell lines B16 culture was the purpose of the present work.
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