SYNTHESIS AND BIOLOGICAL ACTIVITY OF HYDROCHLORID QUINAZOLIN-4-ONE
Saitkulov Foziljon ErgashevichTashkent state agrarian universitet of Uzbekistan, TashkentElmuradov Burkhon ZhuraevichInstitute of Chemistry of Plant Substances Academy of Sciences of the Republic of Uzbekistan, Republic of Uzbekistan, TashkentSapaev Bayramdurdi
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<em>By the interaction of anthranilic acid with formamide, an almost quantitative yield of quinazoline-4-oh was obtained. Optimal reaction conditions were established: temperature 130-140 °C, duration 2 hours. Quinazoline-4-oh hydrochloride was obtained from quinazoline-4-oh by passing hydrogen chloride with 96%
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