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A ResNet-50–UNet Hybrid with Whale Optimization Algorithm for Accurate Liver Tumor Segmentation

Proloy Kumar MondolInstitute of Digital Anti-Aging Healthcare, Inje University, Gimhae-si 50834, Republic of KoreaMd Ariful Islam MozumderInstitute of Digital Anti-Aging Healthcare, Inje University, Gimhae-si 50834, Republic of KoreaHee‐Cheol KimInstitute of Digital Anti-Aging Healthcare, Inje University, Gimhae-si 50834, Republic of KoreaM. H. Al-OnaizanDepartment of Intelligent Systems Engineering, Faculty of Engineering and Design, Middle East University, Amman 11831, JordanDina S. M. HassanDepartment of Information Technology, College of Computer and Information Sciences, Princess Nourah Bint Abdulrahman University, Riyadh P.O. Box 84428, Saudi ArabiaMahmood Al-BahriFaculty of Computing and IT, Sohar University, Sohar 311, OmanMohammed Saleh Ali MuthannaDepartment of International Business Management, Tashkent State University of Economics, Tashkent 100066, Uzbekistan
Diagnosticsjournal2025en
ABI

Аннотация

Objective: Segmentation of liver and liver tumors from 3D medical images is a challenging and computationally expensive task. Organs that are in close proximity may have similar shape, texture, and intensity, which makes it difficult for accurate segmentation. Accurate segmentation of liver tumors is important for diagnosis and treatment planning of liver cancer. Methods: A hybrid model with a U-Net based structure and the Whale Optimization Algorithm (WOA) was proposed. WOA was used to optimize the hyperparameters of the conventional LiTS-Res-UNet to obtain the best segmentation performance of the deep learning model. Results: The LiTS-Res-Unet + WOA hybrid model achieved a performance of 99.54% for accuracy, with a Dice coefficient of 92.38% and a Jaccard index of 86.73% on the benchmark dataset, outperforming state-of-the-art methods. Conclusions: The WOA-based adaptive search space was able to obtain an optimal set of hyperparameters for deep learning model convergence while increasing the accuracy of the model in the proposed hybrid model. The robust performance and clinical applicability of the model in liver tumor segmentation were demonstrated.

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