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A brief overview of cases of breast cancer metastasis to the uterus. A clinical case

G. G. KhakimovaDepartment of Oncology, Pediatric Oncology and Palliative Care of Tashkent State Medical University; Tashkent City Branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology; Department of Oncology, Radiotherapy and Reconstructive Surgery of the N. V. Sklifosovsky Institute of Clinical Medicine at I. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)A. N. RakhmonovDepartment of Oncology, Pediatric Oncology and Palliative Care of Tashkent State Medical UniversityS. I. ErkinovaDepartment of Oncology, Pediatric Oncology and Palliative Care of Tashkent State Medical UniversityShakhnoz G. KhakimovaDepartment of Oncology, Pediatric Oncology and Palliative Care of Tashkent State Medical University; P. A. Herzen Moscow State Medical Research Institute – Branch of the National Medical Research Center of Radiology
Medical alphabetjournal2025
ABI

Аннотация

Breast cancer (BC) can metastasize to many organs, but metastases to the uterus are rare. Breast cancer metastases in the uterus can appear synchronously and metachronously, be asymptomatic or in the form of abnormal vaginal bleeding. Treatment of uterine metastases usually includes total abdominal hysterectomy with bilateral salpingo-oophorectomy in combination with chemotherapy. The long-term prognosis of this course is unclear, but the outcome is mostly unfavorable. This article analyzes 60 patients, published in the literature for the period from 2010 to July 2024. according to nine variables, including: age; morphology of breast cancer; treatment for breast cancer; spread of metastases in the uterus; treatment; out-of-phase distant metastases; survival. The article presents a clinical case of a 53-year-old patient who was diagnosed with metastasis of invasive ductal breast carcinoma into the uterine body. The patient underwent cytoreductive surgery to extirpate the uterus with appendages, followed by hormone therapy with aromatase inhibitors (letrazole).

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