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Transient Psychiatric Disturbances Following Bifrontal Craniotomy for Suprasellar Tumors

Uygun AltibayevNeuro-Oncology, Republican Scientific Center of Neurosurgery, Tashkent, UZBJakhongirmirzo YoldoshevNeuro-Oncology, Republican Scientific Center of Neurosurgery, Tashkent, UZB
Cureusjournal2025en
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INTRODUCTION: Bifrontal craniotomy for suprasellar tumors may lead to the development of transient psychiatric disorders associated with frontal lobe involvement; however, published data on this issue remain limited. METHODS: A retrospective analysis was performed on 70 patients who underwent surgery via the bifrontal approach between 2018 and 2023. Psychiatric evaluation was conducted before and after surgery using the Hospital Anxiety and Depression Scale (HADS). RESULTS: Temporary psychiatric disturbances were observed in 39 of 70 patients (56%): apathy (n=9), depression (n=4), and disinhibition (n=1). Symptom onset occurred on postoperative days 3-7, with a duration of 2-8 weeks. Risk factors included tumor size >4 cm (p=0.03) and operative time >5 hours (p=0.04). Full recovery was noted in all patients within three months. CONCLUSION: Transient psychiatric disorders after bifrontal craniotomy are common but self-limiting in nature. Early psychiatric consultation is recommended.

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