EFFECTS OF THYROID PATHOLOGY ON PREGNANCY COURSE

The thyroid gland is a vital component of the neuroendocrine system. Its functional state significantly impacts reproductive function. The close connection between the thyroid and reproductive systems is confirmed by changes in thyroid function during pregnancy and lactation. The high prevalence of endocrine pathology, the trend toward a further increase in morbidity in women of childbearing age, and the associated adverse outcomes for the woman and her offspring are of great medical and social significance. It is known that the maternal endocrine system significantly influences the growth and development of the fetus and the child after birth. Maternal endocrine pathology can be accompanied by disruption of the maternal-placental-fetal-newborn system. Most often, this is associated with dyshormonogenesis in the pregnant woman, which increases the likelihood of disturbances in the formation and differentiation of organs and tissues, the development of their functions, and the neuroendocrine regulation of the fetus and newborn. The research results also indicate a high risk of developing health problems in later life in children whose mothers suffer from endocrine pathology. In this regard, it is necessary to monitor women of reproductive age with thyroid pathology, timely correction of the endocrine status in order to prevent the development of complications [3]. The most common endocrine pathology is iodine deficiency diseases, the development of which leads to a lack of iodine in the environment. It is known that more than 1 billion people in the world live in areas with iodine deficiency. Thyroid diseases, accompanied by impaired function, often lead to menstrual disorders and decreased fertility. Women with thyroid pathology have a high probability of developing complications during pregnancy and childbirth: early toxicosis, gestosis, intrauterine hypoxia of the fetus, threatened termination of pregnancy, premature birth.

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