Study of the antiallergic activity of the liquid extract «Phytoeczemaderm»

Introduction. The antiallergic activity of the phytospecies «Phytoeczemaderm» recommended for topical therapy of eczema was studied. Material and methods. The study of antiallergic activity was carried out on a model of allergic contact dermatitis caused by skin application of turpentine. As reference preparation were used: antihistamine preparation «Diphenhydramine» gel 1%; glucocorticoid preparation (topical steroid) «Clobetasol» cream 0,05%; zinc preparation «Zinc ointment 10%». Results. During the experiment, it was found, that the test preparation has a reliable antiallergic activity, which is reliably manifested in a decrease in the total allergic reaction, in a reduction in recovery time and in a decrease in the dynamics of the severity of allergic reactions. Also, the study of antiallergic activity showed, that the test preparation has a comparable antiallergic activity with reference synthetic preparation. Conclusion. The foregoing indicates the presence of a reliable antiallergic activity in the «Phytoeczemaderm» preparation, which is comparable to reference synthetic preparations.

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