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THE ROLE OF NEUROTRANSMITTERS IN THE DEVELOPMENT OF NON-EPILEPTIC PAROXYSMS IN CHILDREN

Gаvkhar АbdusattarovaDepartment of Neurology, Pediatric Neurology and Medical Genetics, Tashkent State Medical University, Republic of UzbekistanGulnora TuraevaDepartment of Biological Chemistry, Tashkent State Medical University, Republic of Uzbekistan
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Neurotransmitter imbalance plays an important role in the development of non-epileptic paroxysmal conditions in children. This study examined the contribution of serotonin and dopamine to autonomic and neurodevelopmental disturbances associated with these conditions. Clinical and neurological assessment, including evaluation of autonomic function and instrumental diagnostic methods, demonstrated that decreased serotonin levels were associated with emotional instability, panic attacks, and autonomic dysfunction, while dopaminergic dysregulation was linked to attention deficits, behavioral disturbances, and motor abnormalities. Deficiencies of trace elements were found to increase neuronal excitability and susceptibility to paroxysmal episodes. The findings support the inclusion of neurotransmitter and biochemical assessment in routine diagnostics to improve early identification and individualized treatment of non-epileptic paroxysmal conditions in children.

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