CLINICAL AND PATHOGENETIC DIFFERENCES IN RECURRENT BRONCHITIS ASSOCIATED WITH METABOLIC AND ALLERGIC COMORBIDITIES

Resume. Recurrent bronchitis (RB) is a frequent inflammatory disease of the respiratory tract characterized by repeated episodes of bronchial inflammation and persistent respiratory symptoms. Increasing evidence indicates that the presence and type of comorbid diseases significantly influence the clinical course, pathogenesis, and treatment response of RB. Metabolic disorders and allergic diseases represent two major comorbidity clusters with distinct pathogenetic mechanisms. This study aims to evaluate the clinical and functional differences in recurrent bronchitis associated with metabolic versus allergic comorbidities and to substantiate the need for differentiated, personalized treatment approaches based on comorbidity type. Keywords: recurrent bronchitis, metabolic comorbidity, allergic comorbidity, clinical course, pathogenesis, personalized therapy.

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