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Features of Some Markers of The Inflammatory Response in Patients with Salmonellosis

Nijazova Tajigul AxmetovnaCandidate of Medical Sciences, Associated professor, Department of Infectious and Children’s Infectious Diseases, Tashkent State Medical University, Tashkent, UzbekistanImamova Ilmira AbdullaevnaPhD in Medical Sciences, Associated professor, Department of Infectious and Children’s Infectious Diseases, Tashkent State Medical University, Tashkent, Uzbekistan
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Objective. To study the clinical and laboratory features of the course of salmonellosis in adults. Results. The results of the study showed that the predominant causative agent of salmonellosis in patients older than 45 years is Salmonella enteritidis (more than 75%), with an afebrile course of the disease observed in 30% of cases. Identification of the most appropriate inflammatory response markers for use in an infectious disease inpatient setting, such as C-reactive protein levels and fecal calprotectin assessed dynamically, is becoming increasingly relevant due to the detection of a group of patients with an ongoing inflammatory process. This facilitates the identification of patients who require early rehabilitation. Conclusion. Determination of fecal calprotectin and CRR levels makes a significant contribution to distinguishing patients with a tendency toward a prolonged inflammatory process in the gastrointestinal tract in salmonellosis.

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