Immunofan in the Comprehensive Treatment of Patients with Phlegmon of the Floor of the Mouth

In recent years, an increased incidence of patients with phlegmon of the floor of the mouth has been observed in outpatient dental clinics and maxillofacial surgical departments. According to the literature, secondary immunodeficiency frequently contributes to the development of purulent-septic complications of various diseases, including dental pathologies.A total of 75 patients with phlegmon of the floor of the mouth admitted for inpatient treatment were examined. The patients were divided into two groups. Group 1 (n = 53) received conventional comprehensive therapy. Group 2 patients, as part of comprehensive treatment, additionally received the immunomodulatory agent Imunofan at a dose of 50 µg administered intramuscularly once daily for 5 days.Comparative analysis of treatment outcomes between the conventional and proposed therapeutic regimens revealed significant differences in efficacy and clinical results. The inclusion of the modern immunomodulator Imunofan in the complex therapy of patients with phlegmon of the floor of the mouth resulted in immunological correction, improvement of clinical and laboratory parameters, and a reduction in treatment duration.

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